What is triple negative breast cancer?
About 10-20% of breast cancers — more than one out of every 10 — are found to be triple-negative. If the breast cancer cells tested negative for estrogen receptors (ER-), progesterone receptors (PR-), and HER2 (HER2-), testing negative for all three means the cancer is triple-negative. These negative results mean that the growth of the cancer is not supported by the hormones estrogen and progesterone, nor by the presence of too many HER2 receptors. Therefore, triple-negative breast cancer does not respond to hormonal therapy or therapies that target HER2 receptors. However, other treatment can be used to treat triple-negative breast cancer. Let us see what treatment options are available for triple negative breast cancer.
Treatment for triple negative breast cancer
Chemotherapy is usually given to kill the residual cancer cells after the open surgery. At Modern Cancer Hospital Guangzhou, we offer green chemotherapy, which is safer and brings lesser side effects when compared with intravenous chemotherapy because green chemotherapy targets the tumor directly with higher drug concentration.
Cryotherapy also called cryosurgery, Ar-he knife, is done by releasing Argon gas to lower the temperature and freeze the tumor and the surrounding tissue; then the He gas is released to thaw the frozen tumor thus destroying it in the process.
Interventional therapy is done under the guidance of medical imaging equipment wherein the anti-cancer drugs are injected directly to the blood supplying artery of the tumor which effectively shrinks the tumor. Compared with the traditional chemotherapy, interventional therapy targets the tumor precisely and brings lesser side effects to the body; the drug concentration of anti-cancer drug inside the tumor is much higher than the conventional chemotherapy because it is directly infused into the tumor and so it brings better efficacy.
Targeted therapy is to use drugs or other substances to precisely identify and attack cancer cells, which brings little damage to normal cells. At Modern Cancer Hospital Guangzhou, we provide gene targeted therapy, which targets the root of disease by correcting the abnormal gene. Targeted therapy brings no trauma to the body and lesser side effect to the patients. Targeted therapy can be given before or after surgery.
Chinese medicine therapy
At Modern Cancer Hospital Guangzhou, doctor combines the Chinese medicine therapy with other treatments. Chinese medicine therapy effectively helps you prevent or alleviate the side effects, which may be caused by other treatments. Moreover, Chinese medicine therapy also helps you boost the immune system to prevent cancer recurrence.
Microwave ablation (MWA)
In microwave ablation, a probe will be inserted into tumors, and micro electromagnetic waves will be released to destroy and ablate the cancerous tissues directly. Targeting clearly and affecting intensely the tumor, MWA won’t produce obvious side effects to normal tissues.
The drug called photosensitizer or photosensitizing agent will be infused to the body and the drug will be absorbed mostly by cancer cells after 24 hours to 72 hours. The photosensitizer in the tumor absorbs the light and produces an active form of oxygen that can destroy nearby cancer cells. It well suits patients with advanced cancer or elderly patients and those with poor physical status.
Photon Knife is a technique where the beams of radiation used in treatment are shaped to match the tumor. This uses the targeting information to focus precisely on the tumor, while avoiding the healthy surrounding tissue. This exact targeting makes it possible to use higher levels of radiation in treatment, which are more effective in shrinking and killing tumors in breast.
Nano-knife breaks the membrane of tumor cells with high voltage pulses so that the tumor is destroyed. It is not an open surgery but brings the same effect as surgery does with the advantages of smaller trauma, lesser side effects and quicker recovery.
A personalized treatment plan needs to be made by MDT (multidisciplinary team) after they completely know your case and your willingness. If you want to know what treatment options are suitable for you, you are welcome to consult with us via online consultation or call at 63-02-8221222/63-922-8083333/63-915-4642818. We are here 24/7 to answer your questions.
*Surgery, in addition to the appropriate chemotherapy and radiotherapy, are effective in treating early cancer, but certain patients in late stage of cancer may not be tolerate surgery well as they can be relatively weak. A combination of carefully planned minimally invasive therapy, chemotherapy or radiotherapy can effectively reduce the side effects and discomfort of treatment and may help patient get better efficacy.